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OPEN TRIALS AT CCMC

Study ID

Title

A5971

A Randomized Phase III Study for the Treatment of Newly Diagnosed Disseminated Lymphoblastic Lymphoma or Localized Lymphoblastic Lymphoma

AALL0232

High Risk B-precursor Acute Lymphoblastic Leukemia

AALL0331

Standard Risk B-precursor Acute Lymphoblastic Leukemia

AALL03B1

Classification of Acute Lymphoblastic Leukemia

AALL03N1

Understanding the Ethnic and Racial Differences in Survival in Children with Acute Lymphoblastic Leukemia

AALL0433

Intensive Treatment for Intermediate-Risk Relapse of Childhood B-Precursor Acute Lymphoblastic Leukemia (ALL): A Randomized Trial of Vincristine Strategies

AALL0434

Intensified Methotrexate, Nelarabine (Compound 506U78; IND#52611) and Augmented BFM Therapy for Children and Young Adults with Newly Diagnosed T-cell Acute Lymphoblastic Leukemia (ALL)

AALL05B1

A Children's Oncology Group Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens

AALL06N1

A Study of Neurocognitive Function in Children Treated for Acute Lymphoblastic Leukemia (ALL)

AAML0431

The Treatment of Down Syndrome Children with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Under the Age of 4 Years

AAML0531

A Phase III Randomized Trial of Gemtuzumab Ozogamicin (Mylotarg®) Combined with Conventional Chemotherapy for De Novo Acute Myeloid Leukemia (AML) in Children, Adolescents, and Young Adults

ABTR01B1

A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors

ACNS0121

A Phase II Trial of Conformal RT for Pediatric Patients with Localized Ependymoma, Chemotherapy prior to 2nd Surgery for Incompletely Resected Ependymoma and Observations for Completely Resected, Differentiated, Supratentorial Ependymoma

ACNS0122

A Phase II Study to Assess the Ability of Neoadjuvant Chemotherapy +/- Second Look Surgery To Eliminate All Measurable Disease Prior to Radiotherapy For NGGCT

ACNS0221

A Phase II Study of Conformal Radiotherapy in Patients with Low Grade Gliomas

ACNS0223

Pilot Study Using Carboplatin, Vincristine and Temozolomide for Children Less Than or Equal to 10 Years of Age with Progressive/Symptomatic Low-Grade Gliomas

ACNS0232

Radiotherapy Alone vs. Chemotherapy Followed By Response-based Radiotherapy For Newly Diagnosed Primary CNS Germinoma

ACNS02B1

Pre-clinical Pharmacology in Surgical Brain Tumor Specimens

ACNS02B3

A Children's Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens

ACNS0331

A Study Evaluating Limited Target Volume Boost Irradiation and Reduced Dose Craniospinal Radiotherapy 18.00 Gy and Chemotherapy In Children with Newly Diagnosed Standard Risk Medulloblastoma: A Phase III Double Randomized Trial

ACNS0332

Efficacy of Carboplatin Administered Concomitantly With Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients

ACNS0423

Concurrent Radiation and Temozolomide Followed By Temozolomide and Lomustine in the Treatment of High-Grade Gliomas.

ADVL0524

Phase II Trial of Ixabepilone (BMS-247550), an Epothilone B Analog, in Children and Young Adults with Refractory Solid Tumors

AEPI04C1

Low Birth Weight and Other Risk Factors for Hepatoblastoma

AEWS02B1

A Groupwide Biology and Banking Study for Ewing Sarcoma

AGCT0132

A Phase III Study of Reduced Therapy in the Treatment of Children with Low and Intermediate Risk Extracranial Germ Cell Tumors

AHOD0031

A Phase III Study of Dose-Intensive, Response-Based Chemotherapy and Radiation Therapy for Children and Adolescents with Newly Diagnosed Intermediate Risk Hodgkin Disease

AHOD03P1

Treatment of Children with Newly-Diagnosed Low Stage Lymphocyte Predominant Hodgkin Disease (LPHD)

AHOD0431

Phase III Study for the Treatment of Children and Adolescents with Newly Diagnosed Low-Risk Hodgkin Disease

AHOD0521

A Phase II Study of Bortezomib (Velcade, PS-341, IND # 58443) in Combination with Ifosfamide/Vinorelbine in Pediatric Patients and Young Adults with Refractory/Recurrent Hodgkin Disease

ALTE03N1

Key Adverse Events after Childhood Cancer

ANBL00B1

Neuroblastoma Biology Studies

ANBL00P2

Perinatal Neuroblastoma: Expectant Observation. A Children's Oncology Group Pilot Study

ANBL0421

A Phase II Study of Irinotecan + Temozolomide in Children with Recurrent Neuroblastoma

ANHL04B1

Rare and Cutaneous Non-Hodgkin's Lymphoma Registry

AOST0331

A Randomized Trial of the European and American Osteosarcoma Study Group to Optimize Treatment Strategies for Resectable Osteosarcoma Based on Histological Response to Pre-Operative Chemotherapy

ARAR0331

Treatment of Childhood Nasopharyngeal Carcinoma with Neoadjuvant Chemotherapy and Concomitant Chemoradiotherapy

ARAR0332

Treatment of Adrenocortical Tumors with Surgery plus Lymph Node Dissection and Multiagent Chemotherapy

AREN0321

Treatment of High Risk Renal Tumors

AREN03B2

Renal Tumors Classification, Biology, and Banking Study

AREN0532

Treatment for Very Low and Standard Risk Favorable Histology Wilms Tumor

AREN0533

Treatment of Newly Diagnosed Higher Risk Favorable Histology Wilms Tumors

ARET0332

A Study of Unilateral Retinoblastoma With and Without Histopathologic High-Risk Features and the Role of Adjuvant Chemotherapy

ARST0331

Vincristine, Dactinomycin, and Lower Doses of Cyclophosphamide With or Without Radiation Therapy for Patients with Newly Diagnosed Low-Risk Embryonal/Botryoid/Spindle Cell Rhabdomyosarcoma

ARST0332

Risk-Based Treatment for Pediatric Non-Rhabdomyosarcoma Soft Tissue Sarcomas NRSTS

ARST0431

Intensive Multi-Agent Therapy, Including Dose-Compressed Cycles of Ifosfamide/Etoposide (IE) and Vincristine/Doxorubicin/Cyclophosphamide (VDC) for Patients with High-Risk Rhabdomyosarcoma

ARST0531

Randomized Study of Vincristine, Dactinomycin and Cyclophosphamide (VAC) versus VAC Alternating with Vincristine and Irinotecan (VI) for Patients with Intermediate-Risk Rhabdomyosarcoma (RMS).

D9902

A COG Soft Tissue Sarcoma Biology and Banking Protocol

P9851

Osteosarcoma Biology Protocol: Companion to Group-Wide Therapeutic Studies

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