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Asthma Center

Overview | Staff | About Us | Resources | Easy Breathing | Easy Breathing II

A Study of Asthma in Hispanic Children

Asthma is the most common chronic disease in children. In Hartford, nearly half of all Hispanic children have asthma, especially children of Puerto Rican heritage. Asthma tends to "run in" families and the question is whether it is inherited, that is passed down from one generation to the next through the genes. The Study of Asthma in Hispanic Children attempts to examine whether people with asthma have differences in certain genes that may be more important in determining whether someone has allergies or asthma.

Families of Puerto Rican descent who have a child over 5 years of age with asthma are asked if they would be interested in participating in the study. The first question asked is if both parents are of Puerto Rican heritage and if they are, would both parents be available to participate in the study with their child. If both parents are not available, one parent and a sibling who does not have asthma may participate along with the child who does have asthma.

There is no cost to the family and everything is confidential. No insurance or managed care company will be informed and no names are ever used in the study results.

What is required of the study participants?
  • The family comes to CCMC for a one-time visit.
  • Both parents fill out a very brief health history that asks where they were born and if they have ever had asthma. If there is one parent and a sibling without asthma, then the parent is asked to fill out a brief health history for the sibling.
  • The parents fill out a detailed survey about their child's asthma
  • The child has allergy testing (unless recently done)
  • This child has Pulmonary Function testing (unless that has recently been done).
    Blood samples are drawn from everyone in the family who is participating in the study. EMLA cream, a special cream that numbs the site of the blood test is applied so the children will not feel the blood test needle. The blood is sent to a Harvard University research lab and the lab at Hartford Hospital. Numbers are assigned to the blood samples. The names of family members are not sent with the blood samples.
  • Finally a tiny brush is inserted inside the nose of the child with asthma, just for a second. A few cells from the inside of the nose are brushed away from the mucous membrane for testing.

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